ABOUT US

Our Mission

Fifth Eye’s mission is to provide over-burdened hospital clinicians access to unique, real-time information to:

  • Reduce preventable adverse events: identify patients at risk of deterioration and facilitate early diagnosis and intervention;
  • Reduce length of stay: augment clinical judgment and support timely step-down or discharge decisions.
AHI Traffic Light Simplicity

Our Story

The Challenge

In 2014, an emergency department physician was frustrated with the lack of progress on new tools that could give him a heads up regarding which patients might become unstable and crash. His goal was to reduce the frequency and severity of preventable adverse events.

He challenged a team of physicians, nurses, data scientists, and computer scientists at the University of Michigan to develop a robust and practical means to identify and monitor patients at risk of deterioration – simply, quickly and accurately.

Better by Design

The team’s project goals were twofold. First, create a single metric that correlated well with the current standard in patient monitoring, vital sign-based assessments. Second, add a predictive capability to ultimately get ahead of vital signs.

Design goals included:

  • Real-time results
  • Trended history
  • Easily interpreted
  • “Anytime, anywhere” access
  • Easily implemented into a hospital’s existing workflow
  • Unbiased toward race or other factors

Model inputs: The team identified a variety of continuous, non-invasive physiologic measures that are widely used and automatically collected as candidates. These included SpO2, ECG, Blood Pressure, Heart Rate, and others.

The team looked at these variables alone and in combination. By applying cutting-edge signal processing techniques and machine learning, they were able to extract hidden information from a single ECG Lead II signal to develop a novel analytic that could continuously monitor a patient’s hemodynamic status.

Fifth Eye is Born

Eventually, members of the team formed a company called Fifth Eye. Fifth Eye’s goal was to develop their analytic into medical device software that could be deployed in hospitals.

Fifth Eye continued to work closely with physicians and nurses to develop a product that was not only accurate, but easy to integrate into their existing workflow. They named the company’s first analytic “AHI” (pronounced ‘AH-hee’) which stands for “Analytic for Hemodynamic Instability.”

AHI is able to determine if a patient is stable or unstable in less than 10 minutes, and to provide clinicians with easy access to a continuous trend line updated every two minutes. In March 2021, the company was granted FDA De Novo status to market AHI in the USA.

The AHI System

Fifth Eye continued to search for a means to provide earlier awareness of patients at risk for serious illness. The approach was to create a “leading indicator” to alert clinicians to patients at risk for hemodynamic instability ahead of identification via vital signs.

In December 2021, the company received FDA clearance for its second generation product, the AHI System. In addition to AHI, the AHI System added a new analytic called AHI-PI. “PI” stands for “Predictive Indicator.” As the name suggests, AHI-PI is able to classify patients into one of three categories: low, moderate or high risk for a future episode of hemodynamic instability. Importantly, AHI-PI communicates risk with “traffic light’ simplicity – along with the AHI trend line – for at-a-glance awareness of a patient’s hemodynamic trajectory on any browser enabled device.

Today, the AHI System is deployed at multiple hospitals and is commercially available in the United States.

Our Team

Andrew Malcolmson

ANDREW MALCOLMSON

PRESIDENT & CEO, BOARD MEMBER

Experienced medical device and clinical software executive

JEFF BASCH

CFO

Broad cross-functional management expertise across multiple startups

MARK SALAMANGO

CTO, BOARD MEMBER

25+ years leading software product development teams

ASHWIN BELLE, PHD

CHIEF ANALYTICS OFFICER

Expert data scientist with specialization in signal processing, computational medicine, and machine learning

BRYCE BENSON, PHD

SENIOR DATA SCIENTIST

Expert in bioengineering, cardiac electrophysiology, signal processing, biomedical data analysis

Tom Shehab

TOM SHEHAB, MD

BOARD MEMBER

Over 25 years of diverse healthcare experience as a physician, healthcare executive, and successful venture capitalist

BILL SCHMIDT

BOARD MEMBER

25+ years experience in medical device and health IT sectors, including successfully building and exiting a digital health company and serving as Managing Director of Cultivation Capital’s Life Sciences Fund.

ROBERT KLINE

EXECUTIVE CHAIRMAN, BOARD MEMBER

Serial entrepreneur and executive with over 25 years of experience in the healthcare and life science industries.

Our Partners

AHI is the new standard for detecting and predicting hemodynamic instability. Contact us to learn more.

Thought this was really easy. User friendly. Normally we have in-services; I feel like if you missed that you'd be just fine.

Critical Care/RN

 

 

Nurses don’t have time to update patients' vitals and assessments every two minutes. This gives us a way to see that a patient is stable on a regular basis with easy access.

Step Down/RN

 

 

This tool can help determine where patients go [in the hospital] and how we should treat them, potentially changing admission flow, freeing up capacity and reducing length of stays.

Administrator

 

 

We have a couple of teams dabbling in "early warning" models, but they have not distilled it down to a single ECG lead!

Chief Medical Officer

 

 

It would help me assign patients to nurses, knowing where the “hot-spots” are, and guide me to maintain an equal workflow with my nurses.

Critical Care/Charge RN

 

 

Just install it and they would start to use it.

Critical Care/RN